Boldenone Cypionate Cas# 106505-90-2

The decline in antioxidant enzymes activities can be explained either by introducing free radicals into inactive metabolites or by the direct inhibitory influence of BLD on enzymes function (Barakat et al., 2015). The dose-dependent oxidative kidney stress and damage were recorded following the prolonged ND administration in the mice (Riezzo et al., 2014). In the earlier study, ND-treated mice showed a noticeable increase in peroxidation of lipids and reduced antioxidant enzymes, such as GPx and GSR.

With only £150-£170, you get a well-packed package containing fifty ampoules, each containing 200 mg/ml of this performance accelerator, highlighting our commitment to competitive pricing. Phoenix Remedies’ Boldenate is meticulously crafted with top-grade ingredients. With our rigorous manufacturing standards and commitment to excellence, you can be assured of a product that not only meets expectations but goes far beyond. For medications like Equipoise, it is usually worth considering paying an additional £10-20 to acquire a product that has been tried and tested by thousands, if not millions, of users over the years. The payment method a supplier uses is often a key sign of their trustworthiness.

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The central objective was to elucidate the structures of the main metabolites (phase I and phase II) in urine, with main objective to be further in position to compare boldenone urinary profiles of treated and non-treated animals. Nine metabolites have been identified, only four were present whatever the treatment and the administered boldenone source. Nevertheless, all of them have been detected at least once in non-treated animals which did not permit us to use them as biomarkers of an illegal treatment. At last, but not at least, all metabolites were found mainly glucuro-conjugated, and rarely sulfo-conjugated, with the only exception of 17β-boldenone. Current investigations are showing the absence of 17β-boldenone sulfoconjugate in non-treated animals; that would permit to distinguish non-treated from treated animals with boldione, boldenone and boldenone esters. The control, sesame oil, and VC-treated rats’ kidneys revealed normal histological pictures (Figures 3G,H).

This effect was absent in case of tramadol due to its antidepressant and calming effects. However, when the two drugs were co-administered, tramadol couldn’t counteract the increase in the number of rearings induced by boldenone. In the present study, BLD administration adversely affected antioxidant defense systems in the liver and kidney as indicated by elevated serum MDA level but decreased GSH, GPx, GST, and GSR enzyme activities. These results are compatible with the studies of Neamat-Allah (2014), El-Moghazy et al. (2012), and Tousson et al. (2018).

Administration and Dosage while Using Boldenone Undecylenate

Also, chronic kidney illness remains long asymptomatic before diagnosis in AASs users. Besides, because of its growing muscle mass, creatinine levels are often high in AASs-treated patients, even in the absence of renal injury (Parente Filho et al., 2020). The increase in urea concentration with the AASs use is attributed to the severe reduction in kidney function (Herlitz et al., 2010). Nephrosclerosis, disruptive glomerulosclerosis, and acute renal failure have been observed in AASs users (Taher et al., 2008; Winnett et al., 2011).

The lipid peroxidation marker (MDA) was evaluated in the cortical homogenates of different groups by measuring malondialdehyde level that represents one of the marked metabolites of lipid peroxide. The principal of this method is based on the procedure described by Ruiz-Larrea et al. [41]. It depends on the interaction between malondialdehyde and thiobarbituric acid in acidic medium placed in boiling water bath for 20min. The absorbance of the output derivative was read at 532 nm using UV–visible spectrophotometer.

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Epididymal ductules of group C rabbits were free from mature spermatozoa, and some cauda epididymal ductules contained sloughed germ cells (Figure 3e,f). Made by Pfizer, Equipoise is a substance every horse owner and trainer is raving about. With a chemical structure that mirrors testosterone, this injectable potentiates muscle recovery and growth. Whether your equine has lost its agility due to diseases, undergone surgery, or endured trauma, you can rely on the Equipoise steroid as the ultimate healer and muscle builder. APC-100 is the antioxidant portion of vitamin E (α-tocopherol) and an androgen receptor (AR) inhibitor that may be used in studies related to prostate cancer. Bold-Max ny Maxtreme Pharma is premium solution for those looking to achieve the ultimate in physical and athletic performance.


Serum was separated for assessment of the total serum testosterone according to Demetriou (1987) using solid-phase radioimmunoassay (RIA) kits. This assay was based on presence of a testosterone-specific antibody immobilized to the wall of the polypropylene tube. Thirty white New Zealand mature male rabbits, 9–9.5 months of age, were housed in metal cages. Fed pelleted commercial feed (Ibex Co., Cairo, Egypt) and water was supplied without restriction. Rabbits in all groups received humane care in compliance with the animal care guidelines of the National Institute of Health, and the local ethical committee approved this study.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. Effect of Vitamin C Supplementation on Platelet Aggregation and Serum Electrolytes Levels in Streptozotocin-Induced Diabetes Mellitus in Rats. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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